STRESS DEFICITS IN REWARD BEHAVIOUR ARE ASSOCIATED WITH AND REPLICATED BY DYSREGULATED AMYGDALA-NUCLEUS ACCUMBENS PATHWAY FUNCTION IN MICE

Stress deficits in reward behaviour are associated with and replicated by dysregulated amygdala-nucleus accumbens pathway function in mice

Abstract Reduced reward interest/learning and reward-to-effort valuation are distinct, common symptoms in neuropsychiatric disorders for which chronic stress is a major aetiological factor.Glutamate neurons in basal amygdala (BA) project to various regions including nucleus accumbens (NAc).The BA-NAc neural pathway is activated by reward and aversi

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Neuroticism and adverse life events are important determinants in functional somatic disorders: the DanFunD study

Abstract Several psychological factors have been proposed to be associated with functional somatic disorders (FSD).However, large population-based studies investigating the importance of both personality and adverse life events (ALE) are sparse.This study aimed to investigate the association between FSD and neuroticism and the accumulated number of

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Synset geometry structure model

The goal of formalization, proposed in this paper, is to bring together, as near as possible, the theoretic linguistic problem of synonym conception and the computer linguistic methods based generally on empirical intuitive unjustified factors.Using the word vector representation we have proposed the geometric approach to mathematical modeling of s

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